N.H.P. Cnubben : rechercher sur Z-Library

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Livres
Articles (51)
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1

The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids

Ivonne M.C.M. Rietjens, Marelle G. Boersma, Laura de Haan, Bert Spenkelink, Hanem M. Awad, Nicole H.P. Cnubben, Jelmer J. van Zanden, Hester van der Woude, Gerrit M. Alink, Jan H. Koeman

Journal:

Environmental Toxicology and Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 249 KB

english, 2002

2

Quantitative analysis of Tenecteplase in rat plasma samples using LC–MS/MS as an alternative for ELISA

B.A.P. Buscher, H. Gerritsen, I. van Schöll, N.H.P. Cnubben, L.P. Brüll

Journal:

Journal of Chromatography B

Année:

2007

Langue:

english

Fichier:

PDF, 305 KB

english, 2007

3

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach

Bakker, G. C., van Erk, M. J, Pellis, L., Wopereis, S., Rubingh, C. M, Cnubben, N. H., Kooistra, T., van Ommen, B., Hendriks, H. F.

Journal:

American Journal of Clinical Nutrition

Année:

2010

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2010

4

The urinary metabolic profile of diethylene glycol methyl ether and triethylene glycol methyl ether in Sprague-Dawley rats and the role of the metabolite methoxyacetic acid in their toxicity

Kelsey, Jeffrey R., Cnubben, Nicole H.P., Bogaards, Jan J.P., Braakman, René B.H., van Stee, Leo L.P., Smet, Karen

Journal:

Regulatory Toxicology and Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 1021 KB

english, 2019

5

Regulating human safety: How dose selection in toxicity studies impacts human health hazard assessment and subsequent risk management options

Woutersen, Marjolijn, Muller, Andre, Pronk, Marja E.J., Cnubben, Nicole H.P., Hakkert, Betty C.

Journal:

Regulatory Toxicology and Pharmacology

Année:

2020

Fichier:

PDF, 637 KB

2020

6

A Spectrophotometric Assay for the Detection of 2-Aminophenols in Biological Samples

N.H.P. Cnubben, B. Blaauboer, S. Juyn, J. Vervoort, I.M.C.M. Rietjens

Journal:

Analytical Biochemistry

Année:

1994

Fichier:

PDF, 522 KB

1994

7

Discovery of subtle effects in a human intervention trial through multilevel modeling

Carina M. Rubingh, Marjan J. van Erk, Suzan Wopereis, Trinette van Vliet, Elwin R. Verheij, Nicole H.P. Cnubben, Ben van Ommen, Jan van der Greef, Henk F.J. Hendriks, Age K. Smilde

Journal:

Chemometrics and Intelligent Laboratory Systems

Année:

2011

Langue:

english

Fichier:

PDF, 816 KB

english, 2011

8

Development of an on-line high performance liquid chromatography detection system for human cytochrome P450 1A2 inhibitors in extracts of natural products

Suzanne M.F. Jeurissen, Frank W. Claassen, Jaroslav Havlik, Evelien E. Bouwmans, Nicole H.P. Cnubben, Ernst J.R. Sudhölter, Ivonne M.C.M. Rietjens, Teris A. van Beek

Journal:

Journal of Chromatography A

Année:

2007

Langue:

english

Fichier:

PDF, 403 KB

english, 2007

9

Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study

Marjan J van Erk, Suzan Wopereis, Carina Rubingh, Trinette van Vliet, Elwin Verheij, Nicole HP Cnubben, Theresa L Pedersen, John W Newman, Age K Smilde, van der Jan Greef, Henk FJ Hendriks, Ben van Om

Journal:

BMC Medical Genomics

Année:

2010

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2010

10

Formation of polychlorinated dibenzo-p-dioxins/dibenzofurans on fly ash from precursors and carbon model compounds

R. Addink, P.A.J.P. Cnubben, K. Olie

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 950 KB

english, 1995

11

Metabolism of the insecticide teflubenzuron in rats

KOERTS*, J., SOFFERS, A. E. M. F., DE KRAKER, J.-W., CNUBBEN, N. H. P., RIETJENS, I. M. C. M.

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 348 KB

english, 1997

12

Regioselectivity of Phase II Metabolism of Luteolin and Quercetin by UDP-Glucuronosyl Transferases

Boersma, Marelle G., van der Woude, Hester, Bogaards, Jan, Boeren, Sjef, Vervoort, Jacques, Cnubben, Nicole H. P., van Iersel, Marlou L. P. S., van Bladeren, Peter J., Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2002

Langue:

english

Fichier:

PDF, 95 KB

english, 2002

13

Influence of the Halogen-Substituent Pattern of Fluoronitrobenzenes on Their Biotransformation and Capacity to Induce Methemoglobinemia

Nicole H.P. Cnubben, Ans E.M.F. Soffers, Maria A.W. Peters, Jacques Vervoort, Ivonne M.C.M. Rietjens

Journal:

Toxicology and Applied Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 180 KB

english, 1996

14

Relationships between the Regioselectivity of the Hydroxylation of C4-Substituted 2-Fluoroaniline Derivatives and Their Toxic Endpoints

N.H.P. Cnubben, C.L.van den Berg, I.M.C.M. Rietjens

Journal:

Toxicology and Applied Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 231 KB

english, 1996

15

Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status

Linette Pellis, Marjan J. van Erk, Ben van Ommen, Gertruud C. M. Bakker, Henk F. J. Hendriks, Nicole H. P. Cnubben, Robert Kleemann, Eugene P. van Someren, Ivana Bobeldijk, Carina M. Rubingh, Suzan Wo

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 517 KB

english, 2012

16

Study on the regioselectivity and mechanism of the aromatic hydroxylation of monofluoroanilines

N.H.P. Cnubben, J. Vervoort, C. Veeger, I.M.C.M. Rietjens

Journal:

Chemico-Biological Interactions

Année:

1992

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1992

17

Different metabolic pathways of 2,5-difluoronitrobenzene and 2,5-difluoroaminobenzene compared to molecular orbital substrate characteristics

Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben, Marjon van Haandel, Bozena Tyrakowska, Ans E.M.F. Soffers, Jacques Vervoort

Journal:

Chemico-Biological Interactions

Année:

1995

Langue:

english

Fichier:

PDF, 1.70 MB

english, 1995

18

Comparative MO-QSAR studies in various species including man

Bożena Tyrakowska, Nicole H.P. Cnubben, Ans E.M.F. Soffers, Th. Wobbes, Ivonne M.C.M. Rietjens

Journal:

Chemico-Biological Interactions

Année:

1996

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1996

19

Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells

Jelmer J van Zanden, Liesbeth Geraets, Heleen M Wortelboer, Peter J.van Bladeren, Ivonne M.C.M Rietjens, Nicole H.P Cnubben

Journal:

Biochemical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 237 KB

english, 2004

20

Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2

Jelmer J. van Zanden, Heleen M. Wortelboer, Sabina Bijlsma, Ans Punt, Mustafa Usta, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 360 KB

english, 2005

21

Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin

Jelmer J. van Zanden, Anika de Mul, Heleen M. Wortelboer, Mustafa Usta, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 260 KB

english, 2005

22

Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds

Heleen M. Wortelboer, Mustafa Usta, Jelmer J. van Zanden, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Nicole H.P. Cnubben

Journal:

Biochemical Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 456 KB

english, 2005

23

The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential

Jelmer J. van Zanden, Hester van der Woude, Judith Vaessen, Mustafa Usta, Heleen M. Wortelboer, Nicole H.P. Cnubben, Ivonne M.C.M. Rietjens

Journal:

Biochemical Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 337 KB

english, 2007

24

Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis

Anne-Marie Zuurmond, Angela Koudijs, Benno van El, Robert P. Doornbos, Babs C.T. van Manen-Vernooij, Jacqueline H.M.W. Bastiaans, André H. Penninks, Jolanda H.M. van Bilsen, Nicole H.P. Cnubben, Jeroe

Journal:

Regulatory Toxicology and Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 425 KB

english, 2011

25

Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system

Marlou L.P.S van Iersel, Nicole H.P Cnubben, Natasja Smink, Jan H Koeman, Peter J van Bladeren

Journal:

Biochemical Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 369 KB

english, 1999

26

Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin

Jelmer J. van Zanden, Omar Ben Hamman, Marlou L.P.S. van Iersel, Sjef Boeren, Nicole H.P. Cnubben, Mario Lo Bello, Jacques Vervoort, Peter J. van Bladeren, Ivonne M.C.M. Rietjens

Journal:

Chemico-Biological Interactions

Année:

2003

Langue:

english

Fichier:

PDF, 268 KB

english, 2003

27

Comparative in Vitro–in Vivo Percutaneous Penetration of the Fungicide ortho-Phenylphenol

Nicole H.P. Cnubben, Graham R. Elliott, Betty C. Hakkert, Wim J.A. Meuling, Johannes J.M. van de Sandt

Journal:

Regulatory Toxicology and Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 170 KB

english, 2002

28

The effect of varying halogen substituent patterns on the cytochrome P450 catalysed dehalogenation of 4-halogenated anilines to 4-aminophenol metabolites

Nicole H.P. Cnubben, Jacques Vervoort, Marelle G. Boersma, Ivonne M.C.M. Rietjens

Journal:

Biochemical Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.43 MB

english, 1995

29

Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP

Guido J.R. Zaman, Nicole H.P. Cnubben, Peter J. van Bladeren, Raymond Evers, Piet Borst

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 451 KB

english, 1996

30

Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients

Walter Brand, Maaike E. Schutte, Gary Williamson, Jelmer J. van Zanden, Nicole H.P. Cnubben, John P. Groten, Peter J. van Bladeren, Ivonne M.C.M. Rietjens

Journal:

Biomedicine & Pharmacotherapy

Année:

2006

Langue:

english

Fichier:

PDF, 317 KB

english, 2006

31

Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2

Heleen M. Wortelboer, Michiel G.J. Balvers, Mustafa Usta, Peter J. van Bladeren, Nicole H.P. Cnubben

Journal:

Environmental Toxicology and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 405 KB

english, 2008

32

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1

Raymond Evers, Nicole H.P Cnubben, Jan Wijnholds, Liesbeth van Deemter, Peter J van Bladeren, Piet Borst

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 814 KB

english, 1997

33

Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice

Wopereis, S., Radonjic, M., Rubingh, C., van Erk, M., Smilde, A., van Duyvenvoorde, W., Cnubben, N., Kooistra, T., van Ommen, B., Kleemann, R.

Journal:

Physiological Genomics

Année:

2012

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2012

34

The interplay of glutathione-related processes in antioxidant defense

Nicole H.P Cnubben, Ivonne M.C.M Rietjens, Heleen Wortelboer, Jelmer van Zanden, Peter J van Bladeren

Journal:

Environmental Toxicology and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 333 KB

english, 2001

35

Glutathione-dependent transport of heavy metal compounds by multidrug resistance proteins MRP1 and MRP2

Nicole H.P. Cnubben, Michiel G.J. Balvers, Mustafa Usta, Jelmer J. van Zanden, Peter J. van Bladeren, Ivonne M.C.M. Rietjens, Heleen M. Wortelboer

Journal:

Toxicology Letters

Année:

2006

Langue:

english

Fichier:

PDF, 85 KB

english, 2006

36

Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin

Wortelboer, Heleen M., Usta, Mustafa, van der Velde, Astrid E., Boersma, Marelle G., Spenkelink, Bert, van Zanden, Jelmer J., Rietjens, Ivonne M. C. M., van Bladeren, Peter J., Cnubben, Nicole H. P.

Journal:

Chemical Research in Toxicology

Année:

2003

Langue:

english

Fichier:

PDF, 159 KB

english, 2003

37

Molecular Orbital-Based Quantitative Structure-Activity Relationship for the Cytochrome P450-Catalyzed 4-Hydroxylation of Halogenated Anilines

Cnubben, Nicole H. P., Peelen, Sjaak, Borst, Jan-Willem, Vervoort, Jacques, Veeger, Cees, Rietjens, Ivonnne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

1994

Langue:

english

Fichier:

PDF, 1.57 MB

english, 1994

38

Human Glutathione S-Transferase-Mediated Glutathione Conjugation of Curcumin and Efflux of These Conjugates in Caco-2 Cells

Usta, Mustafa, Wortelboer, Heleen M., Vervoort, Jacques, Boersma, Marelle G., Rietjens, Ivonne M. C. M., van Bladeren, Peter J., Cnubben, Nicole H. P.

Journal:

Chemical Research in Toxicology

Année:

2007

Langue:

english

Fichier:

PDF, 143 KB

english, 2007

39

Human Cytochrome P450 Enzyme Specificity for the Bioactivation of Estragole and Related Alkenylbenzenes

Jeurissen, Suzanne M. F., Punt, Ans, Boersma, Marelle G., Bogaards, Jan J. P., Fiamegos, Yiannis C., Schilter, Benoit, van Bladeren, Peter J., Cnubben, Nicole H. P., Rietjens, Ivonne M. C. M.

Journal:

Chemical Research in Toxicology

Année:

2007

Langue:

english

Fichier:

PDF, 230 KB

english, 2007

40

Human Cytochrome P450 Enzyme Specificity for Bioactivation of Safrole to the Proximate Carcinogen 1‘-Hydroxysafrole

Jeurissen, Suzanne M. F., Bogaards, Jan J. P., Awad, Hanem M., Boersma, Marelle G., Brand, Walter, Fiamegos, Yiannis C., van Beek, Teris A., Alink, Gerrit M., Sudhölter, Ernst J. R., Cnubben, Nicole H

Journal:

Chemical Research in Toxicology

Année:

2004

Langue:

english

Fichier:

PDF, 73 KB

english, 2004

41

Human Cytochrome P450 Enzymes of Importance for the Bioactivation of Methyleugenol to the Proximate Carcinogen 1‘-Hydroxymethyleugenol

Jeurissen, Suzanne M. F., Bogaards, Jan J. P., Boersma, Marelle G., ter Horst, Judith P. F., Awad, Hanem M., Fiamegos, Yiannis C., van Beek, Teris A., Alink, Gerrit M., Sudhölter, Ernst J. R., Cnubben

Journal:

Chemical Research in Toxicology

Année:

2006

Langue:

english

Fichier:

PDF, 154 KB

english, 2006

42

The Göttingen minipig ® as an alternative non-rodent species for immunogenicity testing: A demonstrator study using the IL-1 receptor antagonist anakinra

van Mierlo, Geertje J. D., Cnubben, Nicole H. P., Kuper, C. Frieke, Wolthoorn, Jasja, van Meeteren-Kreikamp, Angelique P., Nagtegaal, Machiel M., Doornbos, Robert, Ganderup, Niels-Christian, Penninks,

Journal:

Journal of Immunotoxicology

Année:

2013

Langue:

english

Fichier:

PDF, 755 KB

english, 2013

43

Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance

Cnubben, Nicole HP, Wortelboer, Heleen M, van Zanden, Jelmer J, Rietjens, Ivonne MCM, van Bladeren, Peter J

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2005

Langue:

english

Fichier:

PDF, 283 KB

english, 2005

44

The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab

van Mierlo, Geertje J. D., Cnubben, Nicole H. P., Wouters, Diana, Wolbink, Gerrit Jan, Hart, Margreet H. L., Rispens, Theo, Ganderup, Niels-Christian, Kuper, C. Frieke, Aarden, Lucien, Penninks, André

Journal:

Journal of Immunotoxicology

Année:

2014

Langue:

english

Fichier:

PDF, 341 KB

english, 2014

45

Assessment of inflammatory resilience in healthy subjects using dietary lipid and glucose challenges

Wopereis, Suzan, Wolvers, Danielle, van Erk, Marjan, Gribnau, Michiel, Kremer, Bas, van Dorsten, Ferdi A, Boelsma, Esther, Garczarek, Ursula, Cnubben, Nicole, Frenken, Leon, van der Logt, Paul, Hendri

Journal:

BMC Medical Genomics

Année:

2013

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2013

46

A single oral dose of a polyglucosamine influences the bioavailability of [9-14C]-Oleic acid in adult female Göttingen minipigs

Cnubben, Nicole H. P., Tel, Shanti L., Hemmes, Marleen A., Langenkamp-Brand, Astrid, Grossouw, Dimitri, Jansen, Harm T., de Bie, Bert T. H. J.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

47

[Studies in Environmental Science] Waste Materials in Construction - Putting Theory into Practice, Proceedings of the International Conference on the Environment and Technical Implications of Construction with Alternative Materials Volume 71 || Leaching Characteristics of Communal and Industrial Sludges

Cnubben, Patrick A.J.P.

Année:

1997

Langue:

english

Fichier:

PDF, 583 KB

english, 1997

48

A Vegetable/Fruit Concentrate with High Antioxidant Capacity Has No Effect on Biomarkers of Antioxidant Status in Male Smokers

van den Berg, Robin, van Vliet, Trinette, Broekmans, Wendy M. R., Cnubben, Nicole H. P., Vaes, Wouter H. J., Roza, Len, Haenen, Guido R.M.M., Bast, Aalt, van den Berg, Henk

Journal:

Journal of Nutrition

Année:

2001

Langue:

english

Fichier:

PDF, 256 KB

english, 2001

49

Use of the kinetically-derived maximum dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management

Heringa, Minne B., Cnubben, Nicole H.P., Slob, Wout, Pronk, Marja E.J., Muller, Andre, Woutersen, Marjolijn, Hakkert, Betty C.

Journal:

Regulatory Toxicology and Pharmacology

Année:

2020

Fichier:

PDF, 848 KB

2020

50

Rebuttal to the letter to the editors regarding Heringa et al. (2020)

Heringa, Minne B., Cnubben, Nicole H.P., Slob, Wout, Pronk, Marja E.J., Muller, Andre, Woutersen, Marjolijn, Hakkert, Betty C.

Journal:

Regulatory Toxicology and Pharmacology

Année:

2020

Fichier:

PDF, 234 KB

2020